Technical informations
Définition : First functional node in the lymphatic irrigation of a tumour.
Interest : Avoid the axilary lymph node dissection and its morbidity.
Targeting sentinel lymph Node :
Isotopic method using technétium-99m Technetium radiomarked substances.
Color method using isosulfan or patented blue.
Isotopic Method :
Injection :
volume = 0.2 ml
activity = 15 up to 110 MBq (0.4 on 3mCi) according to the time period up to the surgery.
Injection technique applied at Jean Perrin Cancer Institute in Clermont-Ferrand.
Results : |Blue dye Method|Isotopic Method|Combination of both methods| |Detection rate from 67 to 98%|Detection rate from 80 to 100 %|Detection rate from 91 to 100%
Preoperative lympho-scintigraphy :